Charles Mullighan is a member of the Department of Pathology at St. Jude Children’s Research Hospital where he is also the Deputy Director Comprehensive Cancer Center and Co-Leader of the Hematological Malignancies Program. He is dedicated to using genomic approaches and experimental modeling to understand the genetic factors driving the pathogenesis and outcome of acute leukemia. His work has identified multiple new subtypes of ALL and genetic alterations contributing to pathogenesis, several of which have entered the clinic as new diagnostic and therapeutic targets. His work has been published in over 150 peer-reviewed publications, including Nature, Nature Genetics, Science and the New England Journal of Medicine.
Dr. Mullighan earned his undergraduate degrees from University of Adelaide in Australia. He earned a M.Sc. from the University of London prior to earning his M.D. from the University of Adelaide. He was a Physician Scientist Postdoctoral Fellow in the Department of Pathology at St. Jude Children’s Hospital prior to joining the Faculty. He is the recipient of several awards, including the American Society of Hematology Joanne Levy, MD, Memorial Award for Outstanding Achievement, being named a Pew Scholar in the Biomedical Sciences, induction into the American Society of Clinical Investigation, and the Meyenburg Prize for Cancer Research.